In Vitro Assessment of Scaffold Cytotoxicity and Biological Efficacy.

Organisation/Company Università Politecnica delle Marche Research Field Medical sciences Researcher Profile Recognised Researcher (R2) Leading Researcher (R4) First Stage Researcher (R1) Established Researcher (R3) Application Deadline 5 Oct 2026 - 13:00 (UTC) Country Italy Type of Contract To be defined Job Status Not Applicable Is the job funded through the EU Research Framework Programme? Not funded by a EU programme Is the Job related to staff position within a Research Infrastructure? No

Offer Description
The project aims to evaluate the in vitro cytotoxicity and bioactivity of novel biomimetic scaffolds. Cell culture models will be used to perform both direct and indirect cytotoxicity assays assessing cell viability, cell death, and material-induced morphological alterations. The bioactivity phase will focus on the ability of the scaffolds to promote osteochondral cell adhesion, proliferation, and differentiation through the evaluation of extracellular matrix deposition and tissue-specific marker expression using morphological, immunohistochemical, and molecular biology techniques. During the 12-month project, experimental protocols will be optimized, data will be collected and statistically analysed, and technical-scientific reports will be prepared. The study will be conducted in accordance with the principles of the 3Rs (Replacement, Reduction, and Refinement), contributing to the preclinical validation of novel scaffolds for regenerative medicine applications.

Italy

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