Senior Technician/Technician of High

1 settimana fa


Milano, Lombardia, Italia Human Technopole Foundation A tempo pieno

APPLICATION CLOSING DATE:
19th of May 2024

The Human Technopole Foundation is looking for a

Senior Technician of High-Throughput Technologies

for the National Facility for Genomics.

The National Facility for Genomics provides state-of-the-art and innovative services in genomics.

Its core mission is to implement robust experimental and analytical workflows to probe all major domains of genomic exploration, including but not limited to the analysis of DNA, RNA, chromatin and other markers of epigenetic and regulatory activity.

These techniques can be applied to diverse areas of biology, with resolution spanning to whole organisms, to tissues or individual cells.

Overall, NF Genomics aims to empower research in all domains of genomics for the Italian scientific community at large.

The National Facilityfor Genomics foresees four Infrastructural Units (IU):

UI1 High Throughput Sequencing

mainly focused on providing state-of-the-art high-throughput sequencing services.

This dedicated unit specializes in delivering top-tier genomics, transcriptomics, and epigenomics analyses, employing the latest protocols for sample processing and sequencing.

UI2 Multi-Omics Technologies

specialized in multi-omics technologies. Its focus extends to providing cutting-edge services in single-cell and spatial multi-omics analysis, as well as long-read sequencing. This Unit closely collaborates with the Tissue Processing Unit and NF-Imaging, specifically dedicated to implementing spatial transcriptomics protocols.

UI3 Technology Development

stays at the forefront of innovation, this dedicated team is committed to methods and technology development.

The highly qualified staff is continuously engaged in the evaluation of new technologies and instruments, considering them for acquisition into our facility.

We specialize in the optimization and scale-up of custom experimental protocols, offering these services to the broader scientific community.

UI4 Computational Genomics


is the computational core of the NF Genomics, the team is dedicated to developing, implementing, and maintaining automated pipelines for the pre-processing and primary data analysis of sequencing data.

This unit closely collaborates with the NF for Data Handling and Analysis.

In the context above outlined, the


Senior Technician of High-Throughput Technologies , reporting directly to the Senior Manager of the IU1, will become part of the team of the High Throughput Sequencing unit of the Genomics National Facility.

At the heart of the IU1 operations are cutting-edge automated systems, carefully designed to continually elevate productive capacity and enhance the cost-effectiveness of services.

This Unit uses advanced technology to streamline processes and accelerate the speed of sample processing and sequencing, integrating high-tech protocols and automation, setting new standards in genomics research.

IU1 transcends the conventional role of a service provider; it stands as a beacon at the technological frontier, constantly striving for innovation, pushing the boundaries of what is possible in genomics, transcriptomics, and epigenomics analyses.

Key tasks and responsibilities

Handle sample and library preparation, including through automation-intensive workstations.
Manage data collection and evaluation support, including the use of a LIMS for data and sample tracking.
Handle next-generation sequencing data, including storage of data and metadata and preparation of sequencing-related files.
Support in the development and implementation of SOPs and/or experimental pipelines.

Participate in key aspects of general Facility management and organization (e.g., managing inventories and stocks of samples, reagents, equipment, and materials).

Report regularly with colleagues and line manager on the flow and timeline of sequencing projects.
Participate in the implementation of sequencing technologies and platforms as sequencing technology progresses.

Mandatory requirements:
Master's degree in a relevant subject, e.g., molecular biology, genetics, biochemistry, or in a related field of the life sciences;
Excellent technical and working knowledge of multiple genomic technologies ( +3 years

of hands-on experience), including documented experience in preparation and sequencing of libraries for the main bulk sequencing technologies (eg. Illumina) for genomics, transcriptomics and epigenomics analyses;
Previous experience in working with automated systems for samples preparation (i.e. nucleic acids extraction, library preparation);
Fluency in English – HT is an international research institute.

Preferred requirements

Good working knowledge of bioinformatics tools to handle, store and prepare files from genomics data.

Organizational and social skills:
Excellent attention to detail, organizational skills, proactive attitude to solve problems and ability to work to deadlines;
Proven communication, team building, and problem-solving skills;
Excellent organizational, communication skills and work ethic;
Ability to independently develop, optimize and deploy research support, as a member of a closely collaborative team.

Application Instructions

Please apply by sending:
i) a CV
ii) a motivation letter in English
iii) names and contacts of at least 2 referees


Questions concerning the role and any queries regarding the terms and conditions should besent to (terms and conditions) (these email address should not be usedto send applications).

Why Human Technopole

HT seeks

scientific excellence , we recruit the best scientific talents through international, open calls;
Our working environment is

international ,

friendly

and

inclusive . Our scientists

work together across disciplines

on research topics of biomedical relevance,

leveraging synergies

between their diverse skillsets and methodological approaches;
We believe that

highly diverse teams yield the best and most innovative results;
We engage in

outward-facing scientific activities

aimed at benefiting the national and international

research community.


Training is also at the heart of our activity, with initiatives and opportunities for our staff, including scientific courses, conferences and workshops.

Main benefits

Welfare plans.
Canteen service.
Work-life balance provisions.
Italian language training for foreigners.
Maternity leave up to 1 year and other support for new parents.
Counseling.
Flexible working hours.
Remote working policy.
Support for relocation.

Special consideration will be given to candidates who are part of the protected categories list, according to L. 68/99.

Number of positions offered : 1

Contract offered :
CCNL Chimico Farmaceutico, Fixed-term -3 years- employee level.

Salary indication:
up to RAL) depending on the seniority.

The position is based in Milan

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