research assistant position at sr-tiget immune core

1 settimana fa


Milano, Lombardia, Italia Ospedale San Raffaele srl A tempo pieno
IRCCS San Raffaele Scientific Institute in Milan, Italy
is looking for a Research Assistant to join the San Raffaele Telethon Institute for Gene Therapy (SR-Tiget) Immune Core.

We are seeking a highly motivated Research Assistant with a strong background in immunological assays and expertise in experimental animal models to work as part of an enthusiastic and dynamic research team investigating multiple immunological aspects associated with in vivo and ex vivo gene and cell therapies for inherited genetic diseases.


Main Activities:
Assays to investigate antigen (Ag)-specific cellular responses (primary cells from several disease models)

Establishment of Ag-specific T cell lines

Differentiation of dendritic cells (DC) and their use for Ag presentation in vitro and in vivo experiments

LV mediated modification of DC, B, and T cells for in vitro and in vivo experiments

Cytokine quantification (Multiplex assay-Luminex)

Determination of Ag-specific antibodies (Abs) titer (ELISA)

Basic Molecular biology and biochemistry (PCR, cloning, western blots, enzymatic activity test)

Flow cytometry (sample preparation/acquisition/analysis, FACS sorting)

Development and optimization of new assays

Mouse work (mice handling, in vivo treatments)

Training of new lab members

Who we are looking for:


Biomedical degree or PhD with strong lab experience; High accuracy, reliability, precision; Experience in T cell functional immune assays; Experience in B cell functional immune assays will be a plus in the selection; Experience in animal handling; High motivation to work in an international, fast-paced environment; Excellent organization skills; Friendly, collaborative, pro-active mindset; Good oral and written English skills.


We offer:


One-year fixed-term contract (assunzione a tempo determinato), renewable; Competitive salary, based on qualifications and experience; A dynamic lab environment and the chance to make an important contribution to biomedical research.


At San Raffaele Scientific Institute, a world-renowned center of excellence for clinical and scientific activities, we believe that considering diversity and promoting an open and inclusive environment is crucial to our success.

We are committed to ensuring that equal employment opportunities are provided and based on merit without regard to age, religion, sex, disability, medical condition, sexual orientation, cultural and social backgrounds, gender identity or expression, national or ethnic origin, or any other legally recognized status entitled to protection under applicable laws.

We offer attractive conditions and rewards appropriate to an internationally competitive research organization.

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