Modulation of the endocannabinoid system in brain tumors

23 ore fa


Messina, Italia Euraxess A tempo pieno

Organisation/Company: Università degli Studi di Messina

Research Field: Biological sciences, Chemistry, Pharmacological sciences

Researcher Profile: Recognised Researcher (R2), Leading Researcher (R4), First Stage Researcher (R1), Established Researcher (R3)

Country: Italy

Application Deadline: 15 Dec 2024 - 23:59 (UTC)

Type of Contract: To be defined

Job Status: Not Applicable

Is the job funded through the EU Research Framework Programme? Not funded by a EU programme

Is the Job related to staff position within a Research Infrastructure? No

Offer Description

In the context of central nervous system disorders, tumors are certainly one of the most widespread and lethal pathologies, and among them, tumors originating from glial cells are the most common and malignant form with a mortality rate that remains high. N-acylethanolamides (NAEs) are endogenous lipid mediators that include the endocannabinoid N-arachidonoylethanolamide (AEA) and its derivatives palmitoylethanolamide (PEA) and oleoylethanolamide (OEA). Recent studies have shown that NAEs are involved in the regulation of several pathological conditions, including immunomodulation, chronic pain, and inflammation. Therefore, based on this, the aim is to evaluate the role of NAEs in cell proliferation, as well as in the modulation of angiogenesis in several brain tumors such as glioma, meningioma, and glioblastoma.

Eligibility of fellows: country/ies of residence:

  • Italy
  • EUROPE

Eligibility of fellows: nationality/ies:

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