Scientist (Synthesis Lab)

For the GNOSIS BY LESAFFRE Business Unit

For over 30 years, Lesaffre has been involved in Human Health & Nutrition as part of its ambition to Better Nourish and Protect the Planet. In November 2018, Lesaffre acquired Gnosis Advanced Biotech and officially combined it with Lesaffre Human Care to form a new Business Unit named Gnosis by Lesaffre.

At Gnosis by Lesaffre, we are committed to cultivating and to delivering nutritional actives, probiotics, and nutritional and functional yeasts that benefit human health and wellbeing, thanks to the power of microorganisms and biotransformation processes like fermentation. Put differently, we explore life to improve living.

Our vision: At Gnosis by Lesaffre, we strive for a world that moves better, digests better, ages better, feels better, and, ultimately, lives better thanks to microorganisms and biotransformation.

We are looking for a Synthesis Laboratory Scientist within the RnA (Research and Application) department.

You will be able to work on your own initiative and as part of a team, therefore good interpersonal skills are essential, as is the ability to be organized, react promptly and meet deadlines when under pressure.

As a Scientist in our Synthesis Team, your main Duties and Responsibilities will be:

• Developing and proposing new process methods for the achievement of synthetic/semisynthetic active principles and impurities or preformulates in the nutraceutical or pharmaceutical field.
• Developing and proposing verification or improvement of purification methods of synthetic, semisynthetic or biosynthetic products, including preparative chromatographic methods.
• Collaborating in defining the specifications of existing or new active ingredients intended for the nutritional or pharmaceutical industry.
• Designing, performing and executing laboratory and Kilolab scale activities aimed at process development and troubleshooting.
• Support for scale-up at plant scale of processes developed in the laboratory.
• Perform in-process analysis according to the most common analytical techniques/instruments (HPLC, IR, UV, DSC).
• Search and review of the scientific and patent literature.
• Activities of collecting, reviewing and managing analytical data related to the search, drafting of research reports and scientific presentations.
• Managing equipment logbooks and maintenance of the laboratory equipment.

• Master's degree in medicinal chemistry (CTF) or chemistry.
• 3+ years of experience in a company in research laboratories dealing with synthetic, semisynthetic, biosynthetic processes in the chemical/pharmaceutical, nutraceutical or biotech industry.
• Competencies and practical experience of the main analytical techniques/instruments (HPLC, GC, KF, IR, UV, LC-MS, NMR).
• Competencies of purification techniques (Solid/liquid and liquid/liquid separation, preparative chromatography, flash chromatography, crystallization, distillation, lyophilization, etc.).
• Experience in scientific literature search and review.

• Fluent in Italian and high level of English (spoken and written).
• Knowledge of techniques and tools for chemical analysis.
• Knowledge of statistics.
• Knowledge of Office tools (Word, Excel, Powerpoint, LIMS/ELN).
• Proactive approach and curious about learning.
• Willingness to travel.