Investigation of the microbiota-immune system-brain tumor axis in preclinical glioma models

Organisation/Company Sapienza Università di Roma Department Dipartimento di Fisiologia e Farmacologia "V.
Erspamer" Research Field Neurosciences » Neurophysiology Researcher Profile First Stage Researcher (R1) Positions Bachelor Positions Application Deadline 25 Nov 2026
- 23:59 (Europe/Rome) Country Italy Type of Contract Temporary Job Status Full-time Offer Starting Date 26 Oct 2026 Is the job funded through the EU Research Framework Programme? Not funded by a EU programme Is the Job related to staff position within a Research Infrastructure? No

Offer Description

Research activity focus on investigating the interactions between the gut microbiota, the immune system, and glioma progression using preclinical mouse models. Experimental procedures include fecal microbiota transplantation, pharmacological treatments, tumor growth monitoring, and assessment of neuroimmune responses. The project also involves cellular and molecular analyses through the isolation and characterization of immune cell populations, cell culture techniques, and functional cytotoxicity assays. In addition, bacterial extracellular vesicles and their role in modulating anti-tumor immune responses are studied. Particular emphasis is placed on understanding the mechanisms underlying microbiota-brain communication and the immune landscape of the tumor microenvironment.