SGLT2 & SIRT1: Hypoxia Signaling in Diabetic Kidney Protection
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Sapienza Università di Roma is seeking a Recognised Researcher (R2) in the Medical sciences field to lead a project investigating the nephroprotective effects of SGLT2 inhibition, focusing on the role of the SIRT1/HIF-1α/HIF-2α signaling axis in diabetic nephropathy.
The study will explore how empagliflozin (EMPA) modulates the balance between HIF-1α and HIF-2α through SIRT1 activation and how these pathways influence cellular adaptation to metabolic and hypoxic stress.
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Torino, Piemonte, Italia Italian Ministry of Education, University and Research Tempo pienoSapienza Università di Roma is seeking a Recognised Researcher (R2) in the Medical sciences field to lead a project investigating the nephroprotective effects of SGLT2 inhibition, focusing on the role of the SIRT1/HIF-1α/HIF-2α signaling axis in diabetic nephropathy. The study will explore how empagliflozin (EMPA) modulates the balance between HIF-1α and...
