Postdoc Position in Structural Biology

1 settimana fa


Genova, Italia Istituto Italiano di Tecnologia A tempo pieno

**Postdoc position in Structural Biology**
- (2300002P)
- Project: _Development of novel small molecules that inhibit the growth of early stage melanoma tumors - Contract number: 23679 - Funded by AIRC (AIRC IG 2019 De Vivo)
- Commitment & contract: collaboration contract, up to 14 months_
- Location: Genova, Italy_

**WHO WE ARE**

At IIT we work enthusiastically to develop human-centered Science and Technology to tackle some of the most pressing societal challenges of our times and transfer these technologies to the production system and society. Our Genoa headquarter is strictly inter-connected with our 11 centers around Italy and two outer-stations based in the US for a truly interdisciplinary experience.

**YOUR TEAM**

The Molecular Modeling and Drug Discovery Research Line is led by Dr. Marco De Vivo, who has extensive experience in computational and medicinal chemistry for drug discovery.

Within the team, your main responsibilities will be to work on the following topics:

- Characterization of the activity and mechanism of action of small molecules _in vitro _using enzyme-based assays.
- Protein crystallization and structure determination.
- Mammalian cell culture techniques and characterization of the mechanism of action of small molecules in mammalian cell-based assays using human cancer cell lines.
- Characterization of protein-protein and/or protein-ligand interaction using biophysical methods like ITC, MST, SPR etc.
- Knowledge and hands-on experience in molecular biology techniques, such as cloning, site-directed mutagenesis, PCR, western blotting, etc.
- Be familiar with imaging techniques and with quantitative image analysis.

This open position is financed by _AIRC - Associazione Italiana per la ricerca sul cancro_ - AIRC - Foundation for Cancer Research in Italy within the “Development of novel small molecules that inhibit the growth of early stage melanoma tumors”.

**WHAT WOULD MAKE YOU SHINE**
- A PhD degree in Biology, Biochemistry, Biophysics, Biotechnology or closely related fields, with a strong record of research productivity.
- Documented experience on structural biology
- A strong publication record, according to your level or experience
- The ability to properly report, organize and publish research data
- Documented experience in coaching junior scientists
- Good command in spoken and written English

**EXTRA AWESOME**
- Good communication skills
- Strong problem solving attitude
- High motivation to learn
- Spirit of innovation and creativity
- Good in time and priority management
- Ability to work in a challenging and international environment
- Ability to work independently and collaboratively in a highly interdisciplinary environment

**COMPENSATION & BENEFITS**
- Competitive salary package for international standards. It will reflect experience and expertise and will be determined after the interview.
- Private health care coverage
- Wide range of staff discounts

**WHAT’S IN FOR YOU?**
- An equal, inclusive and multicultural environment ready to welcome you with open arms. Discrimination is a big NO for us
- We like contamination and encourage you to mingle and discover what other people are up to in our labs
- If paperwork is not your piece of cake, we got you There’s a specialized team working to help you with that, especially during your relocation
- If you are a startupper or a business-minded person, you will find some exceptionally gifted professionals ready to nurture and guide your attitude and aspirations.
- If you want your work to have a real impact, in IIT you will find an innovative and stimulating culture that drives our mission to contribute to the improvement and well-being of society
- We stick to our values Integrity, courage, societal responsibility and inclusivity are the values we believe in They define us and our actions in our everyday life. They guide us to accomplish IIT mission

If you feel this tickles your appetite for change, do not hesitate and apply

**Application’s deadline: May 17**th** 2023**
- We inform you that the information you provide will be used solely for the purposes of evaluating and selecting professional profiles in order to meet the requirements of Istituto Italiano di Tecnologia._
- Your data will be processed by Istituto Italiano di Tecnologia, based in Genoa, Via Morego 30, acting as Data Controller, in compliance with the rules on protection of personal data, including those related to data security._

**Primary Location** GENOVA

**Job** Postdoc

**Organization** Molecular Modeling and Drug Discovery

**Job Posting** Apr 17, 2023, 1:06:31 AM



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