Phd Position in Molecular Oncology

4 settimane fa

Milano, Italia IFOM A tempo pieno

2023/01 Milan

IFOM is an internationally recognized non-profit cancer research institute supported by the Italian Association for Cancer Research (AIRC) based in Milan within a highly dynamic urban environment.

IFOM continuous success is ensured by the recruitment of highly selected undergraduate, graduate and post-graduate researchers from over 24 countries worldwide.

IFOM is hosted within a research campus shared with the European Institute of Oncology and the Italian Institute of Technology.

**About the position**:
Angela Bachi group at IFOM, Milan (Italy), has an opening for a PhD student in molecular oncology to develop a project supported by AIRC IG grant on the role of BACE2 in cancer.

**Ongoing research project**:
Our lab has18 recently discovered that BACE2-dependent amyloid aggregates are produced by melanoma cells. We also found that these amyloid activate mechanotransduction and promote cancer cells proliferation and drug susceptibility (Matafora et al 2020, Farris et al 2021).more recently, we have also collected evidences that BACE2 acticvity is linked to lipid metabolism rewing.
Starting from these observations, the student will develop the project with the aim of better understanding the molecular mechanism linking amyloid production to mechano transduction, lipid metabolism and cancer progression by combining molecular biology and omics techniques.

**Profile description**:
We are looking for a highly motivated PhD student with a biological/biotechnological background and hands on experience on molecular biology, biochemistry and proteomics/metabolomics techniques.

**PhD Programme**:
IFOM ETS/The Open University PhD Programme in Fundamentals of Cancer Biology.

**Educational experience and required computational skills**:
**What we offer/type of contract**:

- PhD for position for four years
- Annual renewal fellowship
- International & interdisciplinary work environment
- Official language: English
- Dedicated support for settling in Milan by IFOM Welcome Office

**Location**:
IFOM is located in Milan - Ripamonti area.
The institute provides high-level scientific education, access to state-of-the-art research facilities and an excellent structure and working environment.

**Contacts details**:

- CV
- Record of their University exams with the relative score
- Experiences in countries different from that where they obtained the undergraduate degree
- List of publications or poster presentations, if any
- English proficiency certificate IELTS, minimum average requirement score 6.5, if you are not a native English speaker or obtained a degree in an English speaking country.

**Deadline**:
27/01/2023

last update: 19/01/23

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