Researcher in Neuronal Cell Biology and Physiology

2 settimane fa

Bolzano Bozen, Italia Company: Eurac Research A tempo pieno

Bozen/Bolzano

Institute for Biomedicine

The Team of Molecular Neurodegeneration investigates cellular and molecular mechanisms underlying the pathogenesis of neurodegenerative and neurological disorders). In 2021 we initiated a project, funded by the Euregio Tyrol-South Tyrol-Trentino, on the study of neurobiological consequences of Covid-19, with the ultimate aim of identifying molecular targets to treat the neurological symptoms of SARS-CoV-2 infection (termed “Neurocovid”). The project is in collaboration with the Medical University of Innsbruck and the Health Service of Trento, for access to patient data.

This position will focus on the differentiation of induced pluripotent stem cells (iPSCs) into cortical neurons, their treatment with Covid-19-relevant material and the investigation of the effects at the neurobiological and neurophysiological levels.

**Tasks**:
The incumbent will perform the following tasks:

- Culture iPSCs and differentiate them in cortical neurons
- Perform molecular and cellular biology assays (qPCR, Western blot, immunofluorescence) and fluorescent and confocal microscopy
- Perform electrophysiological recordings of iPSC-derived neuron via patch-clamp techniques
- Data evaluation and interpretation

**Requirements**:

- Doctoral degree (PhD) in biology or related disciplines
- Excellent laboratory skills in cell and molecular biology
- Excellent written and spoken English
- Excellent team working skills
- Flexibility and willingness to learn and develop
- Previous exposure to electrophysiology is an asset, albeit not necessary
- Availability to start in March 2023

We offer:

- An innovative and multidisciplinary research environment
- A 24-month contract
- Involvement in a highly collaborative project entailing exchanges with the project partners

How to apply:
Progetto Euregio IPN170 “The molecular biology of Neurocovid”
- Company: Eurac Research- Location: Bozen/Bolzano
- Contact person: Mattia Volta
- Phone number: +39 0471 055 483

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