Scientific Leader, In Vitro Metabolism and Pharmacokinetics

2 settimane fa


Pomezia, Lazio, Italia IRBM A tempo pieno
Join a Dynamic Team at IRBM

IRBM is a leading scientific contract research organization (CRO) dedicated to accelerating breakthroughs in drug discovery. Our unified research facility in Pomezia, Italy, enables collaborative innovation and efficient progress from initial concept to pre-clinical candidate.

With a strong track record of contributing to approved drugs and an internal pipeline of oncology and other therapeutic assets, IRBM fosters deep collaborations and leverages decades of expertise from global institutions. Our comprehensive in-house capabilities support partners in achieving key milestones and progressing towards clinical readiness, positioning IRBM as a major player in driving innovation in the pharmaceutical and biotech fields.

Senior Leadership Opportunity

We are seeking an experienced Director, Drug Metabolism and Pharmacokinetics to oversee and manage in vitro and in vivo PK, ADME, and bioanalytical assays. The successful candidate will lead a team of over 25 scientists responsible for designing, executing, analyzing, interpreting, and communicating PK/ADME studies to support drug development.

Key Responsibilities:

  1. Lead Scientific Efforts: Characterize metabolic fate and pharmacokinetic properties of drug candidates to inform lead optimization.
  2. Represent DMPK: Participate in cross-functional development project teams, including preparing project strategies and development plans.
  3. Stay Current: Ensure the DMPK team applies emerging concepts and technologies for issue resolution.
  4. Quantitative Bioanalysis: Implement and manage quantitative bioanalysis of plasma and other biological matrices.
  5. Preclinical Drug Metabolism: Oversee internal and outsourced pre-clinical drug metabolism and PK activities.
  6. Strategic Leadership: Provide scientific and strategic leadership, urgency, and business acumen to grow and progress IRBM's mission.

Requirements:

  1. PhD or equivalent degree in Pharmaceutical Sciences, Molecular Biology, Chemistry, Biochemistry, or Pharmacology with experience in drug discovery.
  2. At least 8+ years of relevant industry experience.

To apply, please follow the instructions provided for submitting your application. IRBM is an equal opportunities employer and welcomes applications from all qualified candidates.



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