Senior Research Associate
2 giorni fa
We are seeking a highly motivated and experienced Senior Research Associate to join our Oncology Unit at IRBM. As a key member of our team, you will play a crucial role in supporting our drug discovery efforts by executing experiments to test biological hypotheses, identifying new targets, and defining the mechanism of action of new molecular entities in Oncology.
Key Responsibilities:
- Design, execute, and analyze experiments to test biological hypotheses and identify new targets
- Develop and maintain primary cell lines and organoids
- Screen small molecule ligands in microplate-based assay formats to drive Structure-Activity Relationship on purified protein using manual and automated systems
- Develop and perform cell-based assay enzymatic (determine enzyme activity and kinetics) and substrate binding assays independently or with other team members as instructed
- Provide technical support and supervision to other laboratory members, including introduction and teaching of laboratory techniques and support on the use of lab equipment
Requirements:
- Master's degree in biology, biochemistry, biotechnology, or other biological science area
- Minimum 2 years of postgraduate research experience with an in-depth knowledge of cancer biology and cell-based assays
- Experience with standard molecular biology and biochemical techniques (e.g., cloning, nucleic acid and protein isolation from human and animal tissue samples, PCR/qPCR, and Western blot)
- Experience with relevant experimental techniques to modulate gene expression, such as CRISPR, lentiviral transduction, RNAi, shRNA, etc.
- Experience in bacterial transformation, and restriction enzyme analysis
- Excellent organizational and communication skills
- Proficiency in IT Tools: MS Office Software (Word, Outlook, Excel, PowerPoint), GraphPad Prism (or similar) for data analysis
- Ability to multitask with emphasis on accuracy and attention to details
- Flexible, proactive, efficient, and able to work independently with a problem-solving attitude
- Strong team player, high-energy, and positive personality
- Working knowledge of English is mandatory
Desirable Qualifications:
- 2+ years of experience in biotech/pharma company with expertise in drug discovery would be a strong asset
- Experience establishing and maintaining primary cell lines and organoids
- Experience in screening small molecule ligands in microplate-based assay formats to drive Structure-Activity Relationship on purified protein using manual and automated systems
We thank all applicants for their interest. Candidates selected for interviews will be contacted.
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