Neural Modeler Post-Doc

Job Opportunity: Eurac Research is seeking a highly motivated Postdoctoral Researcher to join our team in the Institute for Biomedicine. The successful candidate will work on iPSC-derived human neuronal disease modeling and development of high-throughput molecular assays within the CELLMED project, funded by the European Regional Development Fund.

About the Project: The CELLMED project aims to predict, slow, or preempt illness progression by understanding genetic, biological, environmental, and lifestyle factors. Our team employs state-of-the-art labs and innovative management to span the full translational research cycle, from data generation to functional characterisation of molecular disease mechanisms.

Responsibilities: The researcher will contribute to the creation of an iPSC-derived platform of nervous system models for Parkinson's disease research, which can partially reduce the need for animal experiments and can be used for screening efforts in collaboration with academic and industrial partners. Key tasks include:

• Establishment and characterization of human iPSC-derived cell models, including 3D cultures and organoids for neurological diseases
• Cell-culture, biochemical, molecular, and functional assays
• Confocal imaging and data analysis
• Supervision of students and preparation of presentations, manuscripts, and grant writing

Requirements: PhD in neuronal cell biology/physiology or related disciplines with proven experience in neurobiological research. The ideal candidate should have experience deriving iPSCs and reprogramming to central/peripheral neurons, as well as using cellular 3D systems, including organoids or organ-on-chip. Experience in RNA and protein expression analysis, end-point functional assays, and confocal microscopy is also required. Excellent written and spoken English is essential.

What We Offer: An innovative and multidisciplinary research environment, a three-year contract, and a salary proportional to experience.