Study Of Mitochondrial Transfer Into Thermogenic Tissues During Aging

Organisation/Company Università degli Studi di Roma Tor Vergata
- Dipartimento di Biologia Research Field Biological sciences Researcher Profile Recognised Researcher (R2) Leading Researcher (R4) First Stage Researcher (R1) Established Researcher (R3) Application Deadline 31 Oct 2026
- 23:59 (UTC) Country Italy Type of Contract To be defined Job Status Not Applicable Is the job funded through the EU Research Framework Programme? Not funded by a EU programme Is the Job related to staff position within a Research Infrastructure? No Offer Description Aging undermines the body's ability to adapt, particularly the function of thermogenic adipose tissue (t-AT), which is essential for metabolism. As we age, the quality of mitochondria declines, leading to metabolic disorders like insulin resistance and type 2 diabetes When adipocytes are stressed, they release damaged mitochondria that are quickly cleared by macrophages. Theseimmune cells transform into "M2" macrophages, which have anti-inflammatory properties. Recent discoveriesindicate that M2 macrophages can