Fellow Center for Accelerating Leukemia/lymphoma Research

2 settimane fa

Rozzano, Italia Humanitas A tempo pieno

Località: Rozzano, IT, 20089

The project will take place within the frame of an international collaborative research project supported by Italian Agency for Cancer Research (AIRC) - PI Dott. Gabriele Todisco.
We are looking for a curious, motivated, and passionate junior scientist with experience in molecular biology techniques. You must be a good team player but still retain enough independence to explore your results from a conceptual standpoint.
**Responsabilities**
**Requirements**:

- Excellent team-working capabilities even with colleagues from different research areas and international backgrounds;
- Strong self-motivation, commitment and proactive approach;
- Ability to meet deadlines and work autonomously in rapidly changing environments;
- Curiosity and ability of stepping outside your comfort zone.

**Selected References**
- Integrated Genomic and Transcriptomic Analysis Improves Disease Classification and Risk Stratification of MDS with Ring Sideroblasts. Todisco G et al, Clin Cancer Res. 2023 Oct 13;29(20):4256-4267.
- Co-mutation pattern, clonal hierarchy, and clone size concur to determine disease phenotype of SRSF2P95-mutated neoplasms. Todisco G et al, Leukemia. 2021 Aug;35(8):2371-2381.
- Pseudouridine-modified tRNA fragments repress aberrant protein synthesis and predict leukaemic progression in myelodysplastic syndrome. Guzzi N et al, Nat Cell Biol. 2022 Mar;24(3):299-306.
- ZBTB33 is mutated in clonal hematopoiesis and myelodysplastic syndromes and impacts RNA splicing. Beauchamp EM et al, Blood Cancer Discov. 2021 Sep;2(5):500-517

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