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NGS Staff Scientists

9 ore fa


Udine, Friuli Venezia Giulia, Italia IGA Technology Services A tempo pieno

About IGATech

IGATech is a leading Italian provider of next-generation sequencing services, active since 2009 and collaborating with hundreds of academic and industrial clients worldwide. With more than 50,000 samples processed annually, we support cutting-edge research through advanced sequencing technologies and state-of-the-art bioinformatics.

Our in-house infrastructure includes molecular biology laboratories, sequencing platforms (Illumina, Element Biosciences, Oxford Nanopore), automation systems, and a dedicated HPC environment. We actively participate in European research projects and collaborate with universities, research institutes, hospitals (IRCCS), and private companies in biotech, biopharma, and agri-genomics.

The Position

We are looking for a
Junior Scientist
to join our
Single-Cell, Exome & Epigenomics team
, with a role strongly focused on
cell and tissue manipulation
and
sample preparation for advanced NGS applications
.

The selected candidate will contribute to the
3-DIMENSION project
, funded by the Italian Fund for Applied Sciences (FISA

This role operates
upstream of sequencing
, ensuring the quality, integrity, and reproducibility of cellular and tissue samples that are critical for single-cell, epigenomic, and exome experiments. Prior experience in NGS is a plus, but
strong hands-on skills in cell and tissue biology are the top priority
. NGS-specific protocols will be learned through structured training.

This position is ideal for scientists who want to work with frontier technologies in a real applied setting, where experimental rigor and data quality truly matter.

Key Responsibilities

Cell and tissue handling

  • Preparation, manipulation, and storage of biological samples (fresh, cryopreserved, FFPE).
  • Mechanical and enzymatic tissue dissociation, with protocol optimization based on sample type.
  • Cell counting, viability assessment, and quality evaluation of cell suspensions.
  • Cell enrichment, cleaning, and selection (filtration, gradients, external sorting collaborations).
  • Handling of low-input and biologically critical samples.

Single-cell and epigenomics sample preparation

  • Sample preparation for single-cell applications (scRNA-seq, scATAC-seq, multiome).
  • Nuclei preparation for epigenomic assays.
  • Support for exome sequencing and low-input DNA/RNA workflows.
  • Pre-library quality control (quantity, integrity, contamination).

NGS and molecular biology

  • NGS library preparation (single-cell, exome, epigenomics) using standard and custom protocols.
  • Supporting molecular biology techniques (PCR, qPCR, clean-ups, normalization).
  • QC of DNA, RNA, and libraries (Bioanalyzer, TapeStation, Qubit or equivalent).
  • Coordination with the sequencing team for sample planning and traceability.

Quality, organization, and continuous improvement

  • Accurate documentation and full sample traceability.
  • Contribution to protocol optimization and experimental troubleshooting.
  • Close collaboration with application scientists, bioinformaticians, and platform managers.
  • Support for standardization and maintenance of internal quality standards.

Requirements

Education

  • MSc or PhD in Biotechnology, Biology, Molecular Biology, or related fields.

Core skills (priority)

  • Hands-on experience with cell and/or tissue manipulation.
  • Familiarity with tissue dissociation and cellular sample handling.
  • Ability to work with delicate and low-input biological material.
  • Strong awareness of sample quality as a determinant of data quality.

NGS experience (preferred)

  • Experience with NGS library preparation.
  • Knowledge of single-cell, exome, or epigenomics workflows.
  • Familiarity with commercial NGS kits and platforms.
  • Experience with laboratory automation is a plus.

Additional skills

  • Good laboratory practices and safety compliance.
  • Ability to work in SOP-driven and quality-oriented environments.
  • Fluent Italian and good technical-scientific English.

Personal attributes

  • Precision and attention to detail.
  • Methodical mindset and responsibility for produced data.
  • Ability to work in multidisciplinary teams.
  • Operational autonomy combined with openness to technical discussion.
  • Experimental problem-solving attitude and scientific curiosity.
  • Ability to manage priorities without compromising quality.

What We Offer

  • 24-month fixed-term contract.
  • CCNL Chimico-Farmaceutico, level C2.
  • Gross annual salary range:
    €30,000 – €35,000
    , based on experience.
  • Welfare benefits and meal vouchers.
  • Full-time (40 h/week) or part-time (35 h/week).
  • Workplace: Udine – "Luigi Danieli" Science and Technology Park.
  • Progressive specialization in advanced single-cell and epigenomics technologies.