Post-Doctoral Research Scientist | Buffa'S Laboratory

OverviewIFOM is an internationally recognized non-profit cancer research institute supported by the Italian Association for Cancer Research (AIRC) based in Milan within a dynamic urban environment.IFOM recruits highly competitive researchers worldwide, with representation from over 24 countries.Labs are hosted within a research campus shared with the European Institute of Oncology and the Italian Institute of Technology.IFOM is committed to a safe and inclusive work environment, offering equal job opportunities to all qualified candidates.We seek for our Institute: Post-doctoral Research Scientist | Buffa's laboratory.Position DescriptionThe Buffa Lab is seeking a highly motivated postdoctoral scientist to work on the project entitled "Single-cell AI-reconstructed gene network rewiring in hypoxia to dissect mechanisms of cancer progression and metastasis (REWIRE)."The laboratory uses systems biology approaches to understand how cancer evolves and responds to treatment, and how the tumor microenvironment affects this process.The project aims to advance understanding of cell reprogramming under early and chronic hypoxia in multiple experimental models, with a focus on CRISPR and single-cell sequencing.The project will involve perturbation experiments in cell lines, organoids and single-cell next-generation sequencing approaches.Profile Description & RequirementsThe ideal candidate will possess robust communication skills, self-motivation, and the ability to work autonomously.Additionally, they should foster collaboration and constructive contributions within IFOM's scientific environment.Proficiency in advanced biochemical/molecular/cell biology techniques;Demonstrable knowledge and experience of current omics and CRISPR assays;Publications in internationally recognized journals;Presentations of scientific findings at conferences, seminars or other relevant meetings;Ability to work independently and as part of a team;Ability to take the lead and manage small research projects when required;Attention to detail and the ability to keep accurate and ordered experimental data;Reliability and flexibility;Proficiency in English for speaking and writing.English is the working language at the Institute.Required SkillsPhD or equivalent degree in Molecular Biology, Genetics, Biotechnology, or a closely related field;Research experience in genomics, functional genomics, and perturbation-based assays;Proficiency in advanced molecular biology techniques;Demonstrated experience with CRISPR-based screens;Demonstrate experience with transcriptomics, single-cell genomics or proteomics;Proven track record of publications in peer-reviewed journals;Ability to work independently as well as collaboratively within a team;Additionally Desired SkillsFirst-author publication in internationally recognised journals;Having obtained previous grant funding;Experience with other biochemical techniques, e.g. shRNA;EducationalPhD in molecular or cellular biology or a related field.What We OfferInternational work environment, flextime, and benefits including discounts for gym, pharmacy, psychology service and various shops around IFOM area; bar and canteen inside the campus with lunch benefit; company nursery; continuous support to candidates and their families (including housing, schooling, registration to the national health system, work permit) thanks to the Welcome Office, Medical Service, laptop, cafeteria service and tax declaration.Type of ContractAnnual renewable fellowship (post-doc) or co.co.co contract.The candidate will be offered a competitive salary commensurate with skills and experience.Location & ContactLocation: Pavia, Lombardy, ITALY (Buffa Laboratory).Interested candidates should send a motivation letter, CV and contact information for at least two references to:This announcement is addressed to both sexes pursuant to laws ****** and ****** and to people of all ages and nationalities pursuant to Legislative Decrees ****** and ******.Privacy & Data ProtectionArticle 13 of EU Regulation ********: We inform you that archiving and processing of data referring to you are carried out by IFOM - Istituto Fondazione di Oncologia Molecolare ETS to perform the recruitment process.The legal basis for processing is the necessity to take steps at the request of the data subject prior to entering into a contract.Your data may be communicated to third parties located outside the EU for recruitment purposes.IFOM has obtained the necessary guarantees to transfer data in compliance with GDPR Chapter V. Resumes received will be deleted at the end of the calendar year following receipt; if you are still interested you may re-send.To exercise your rights, contact the Data Controller at IFOM - Istituto Fondazione di Oncologia Molecolare ETS, via Adamello 16, Milano, IFOM has appointed a Data Protection Officer (DPO) who can be contacted at#J-*****-Ljbffr