Trainee Post-Lauream In Biological Sciences/ Biotechnology For The Identification Of Novel Mole[...]

30 minuti fa


Bolzano, Italia Altro A tempo pieno

Institute for Biomedicine Short description of the position: The Institute for Biomedicine, located at Bolzano's NOI Techpark, is a key component of Eurac Research, dedicated to improving health through precision prevention research.This interdisciplinary effort seeks to predict, slow or preempt illness progression by understanding genetic, biological, environmental, and lifestyle factors.Utilizing a decade-long population study in collaboration with the South Tyrolean Healthcare Service, the institute offers access to extensive data and biological materials suitable for such research.With a focus on neurological, cardiovascular, and metabolic health, the team employs state-of-the-art labs and innovative management to span the full translational research cycle, from data generation to potential clinical application.In its focus area "Mitochondrial function and neuronal disease modelling" the Translational Genomics group is looking for a Trainee post lauream to work on mitochondrial targets for Parkinson's disease (PD).Specifically, the team investigates genes and pathways that contribute to the pathological processes of PD by disrupting mitochondrial function.Using appropriate neuronal models that include iPSC-derived neurons grown in 2D and 3D culture, we are assessing molecular phenotypes and testing specific targets and pathways for developing interventional strategies and slowing down the disease process.The selected candidate will join a project devoted to realizing a high-throughput screen for the identification and validation of novel molecular targets.The position is open for students post lauream with a master's degree in science (cell biology, biotechnology, neuroscience or related disciplines) for a period of 10 months (graduation no more than 12 months before the start of the internship).Tasks:iPSC cultureDifferentiation of iPSCs into neuronal culturesReal time-PCR and Western blotImmunofluorescence and confocal imagingHigh throughput imagingBiochemical assaysMolecular cloning techniquesGene editing by CRISPR-CasRequirements:Molecular and cellular biology basesExperience in cell culture work as well as in basic molecular laboratory techniquesPrevious experience in iPSC culture and differentiation will be an advantageGood knowledge of English; knowledge of either German or Italian language is an advantageWell-developed social skills, a hands-on attitude and ability to work in a teamWilling to develop new skills and explore novel ideasWe offer:International environment and engaged colleaguesTraining in a broad range of cell and molecular biology techniquesInternship compensationHow to apply:Interested candidates should submit their application (CV, cover letter and further relevant documents) by **********.#J-*****-Ljbffr



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