Germline MPN Genomics Investigator
10 ore fa
pavia, lombardia, Italia
Italian Ministry of Education, University and Research
Tempo pieno
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Università di Pavia is seeking a researcher for a project in medical sciences with three main aims: (1) evaluate the prevalence of germline mutations in DNA repair genes in MPN and their correlation with the clinical phenotype; (2) explore in hematopoietic stem and progenitor cells how germline CHEK2 variants synergize with JAK2 driver mutations to promote clonal expansion and disease manifestation; (3) test whether familial surveillance can preemptively identify solid cancers and myeloid
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