POST-DOCTORAL POSITION ON AN ERC-FUNDED PROJECT

4 settimane fa


Milano, Italia Gruppo San Donato A tempo pieno

POST-DOCTORAL POSITION ON AN ERC-FUNDED PROJECT (SR-TIGET) IRCCS San Raffaele Scientific Institute in Milan, Italy, is looking for a highly motivated Postdoctoral Fellow to join the Liver Gene Therapy Unit, SR-Tiget . The goal of our lab is to study liver dynamics during growth and homeostasis to devise permanent in vivo genetic engineering of hepatocytes for the treatment of metabolic diseases in pediatric patients. To this aim, we combine single-cell, organoids, and multiomic analyses, including the latest-generation spatial transcriptomics, together with advanced genetic engineering tools. The ERC-funded project builds on our recent findings that most hepatocytes are quiescent during liver growth, and only a fraction of them generate most of the adult tissue. We aim now to characterize molecular programs of mouse and human proliferating and quiescent hepatocyte subsets and assess their susceptibility to in vivo lentiviral gene delivery and targeted genome editing. Main activities Characterization of molecular and functional heterogeneity of hepatocytes during liver growth In vivo genetic modification of hepatocytes Data analysis and critical interpretation of the results Discussion of project results at internal and external meetings Training of younger fellows in the lab Who we are looking for Ph.D. in life sciences Proven track record of publications in recognized journals Documented experience in molecular and cellular biology Previous experience with mouse models or gene therapy is a plus Work details Type of contract: renewable collaboration Duration: 2 years Place of work: IRCCS San Raffaele Hospital, Via Olgettina, number 60 - Milan (Italy) San Raffaele Scientific Institute is committed to equal employment opportunities and to promoting diversity and inclusion. We ensure equal opportunities based on merit regardless of age, religion, sex, disability, medical condition, sexual orientation, cultural and social backgrounds, gender identity or expression, national or ethnic origin, or any other legally protected status. We offer attractive conditions and rewards appropriate to an internationally competitive research organization. J-18808-Ljbffr



  • Milano, Italia Ospedale San Raffaele A tempo pieno

    IRCCS San Raffaele Scientific Institute in Milan, Italy, is looking for a highly motivated Postdoctoral Fellow to join the Liver Gene Therapy Unit, SR-Tiget.The goal of our lab is to study liver dynamics during growth and homeostasis to devise permanent in vivo genetic engineering of hepatocytes for the treatment of metabolic diseases in pediatric...

  • Post-doctoral Fellow

    4 giorni fa


    Milano, Italia Ospedale San Raffaele srl A tempo pieno

    IRCCS San Raffaele Scientific Institute in Milan, Italy, is looking for a Post-doctoral Fellow to join the Imaging of Gene Regulation lab, led by Prof. Davide Mazza. The Imaging of Gene Regulation lab develops and applies innovative microscopy approaches to dissect in a quantitative manner how gene expression is controlled in living cells. In particular, we...

  • Post-doctoral Position

    2 settimane fa


    Milano, Italia Ospedale San Raffaele srl A tempo pieno

    **Post-Doctoral Position - Tissue Regeneration and Homeostasis**: Our main interest is to gain a deeper understanding of the cellular and molecular mechanisms that coordinate tissue regeneration and homeostasis. We combine in vivo mouse models with molecular, cellular and imaging procedures to unravel mechanistic insights underlying the regenerative process...


  • Milano, Italia University of Groningen A tempo pieno

    Postdoc Opportunity: Department of Social and Political Science at the University of Milan The Department of Social and Political Science at the University of Milan is looking to recruit a post-doctoral researcher. The position is fully funded for two years and can be renewed for a further two years. The researcher will work directly with Professor...


  • Milano, Italia The International Society For Bayesian Analysis A tempo pieno

    Postdoc position at Bocconi University (Milan, Italy)Postdoc position available at Bocconi university funded by the ERC Starting Grant "Provable Scalability for high-dimensional Bayesian Learning", under the supervision of Giacomo Zanella.Deadline for applications: 2nd February ****Starting date of the position: September **** (flexible)Duration: starting...


  • milano, Italia The International Society for Bayesian Analysis A tempo pieno

    Postdoc position at Bocconi University (Milan, Italy) Postdoc position available at Bocconi university funded by the ERC Starting Grant “Provable Scalability for high-dimensional Bayesian Learning”, under the supervision of Giacomo Zanella. Deadline for applications: 2nd February 2025Starting date of the position: September 2025 (flexible)Duration:...


  • milano, Italia The International Society for Bayesian Analysis A tempo pieno

    Postdoc position at Bocconi University (Milan, Italy)Postdoc position available at Bocconi university funded by the ERC Starting Grant “Provable Scalability for high-dimensional Bayesian Learning”, under the supervision of Giacomo Zanella.Deadline for applications: 2nd February 2025Starting date of the position: September 2025 (flexible)Duration:...


  • milano, Italia The International Society for Bayesian Analysis A tempo pieno

    Postdoc position at Bocconi University (Milan, Italy)Postdoc position available at Bocconi university funded by the ERC Starting Grant “Provable Scalability for high-dimensional Bayesian Learning”, under the supervision of Giacomo Zanella.Deadline for applications: 2nd February 2025Starting date of the position: September 2025 (flexible)Duration:...


  • Milano, Italia The International Society for Bayesian Analysis A tempo pieno

    Postdoc position at Bocconi University (Milan, Italy) Postdoc position available at Bocconi university funded by the ERC Starting Grant “Provable Scalability for high-dimensional Bayesian Learning”, under the supervision of Giacomo Zanella. Deadline for applications: 2nd February 2025 Starting date of the position: September 2025 (flexible) Duration:...


  • Milano, Italia The International Society for Bayesian Analysis A tempo pieno

    Postdoc position at Bocconi University (Milan, Italy) Postdoc position available at Bocconi university funded by the ERC Starting Grant "Provable Scalability for high-dimensional Bayesian Learning", under the supervision of Giacomo Zanella. Deadline for applications: 2nd February 2025 Starting date of the position: September 2025 (flexible) Duration:...