Senior Scientist, Clinical Pharmacology

2 giorni fa


Italia Alnylam Pharmaceuticals Inc. A tempo pieno

Job Description - Senior Scientist, Clinical Pharmacology (240055)

Overview

The Senior Scientist, Clinical Pharmacology position will support a rapidly expanding clinical portfolio of promising RNAi therapeutics. The candidate in this position should be well versed in PK and PD with strong ability to critically evaluate and interpret data, conduct noncompartmental analysis, and PKPD modeling. In this role, the candidate is expected to have a strong critical thinking ability with good oral and written communication skills.

Summary of Key Responsibilities

  • Represent Clinical Pharmacology and provide PKPD support and guidance to clinical stage project teams.
  • Lead the analysis, interpretation, integration and reporting of clinical pharmacokinetic & pharmacodynamic data.
  • Conduct PK/PD analyses to guide development decisions on project teams.
  • Provide PKPD input for regulatory submissions such as briefing documents, IND, CTA and NDA.
  • Prepare appropriate documents or sections of clinical protocols, Investigator Brochures, Clinical Study Reports with respect to Clinical Pharmacology studies or data.
  • Preparation of abstracts and manuscripts for publication.
  • Closely partner with Research, Bioanalytical, Clinical functions, Regulatory, Project Management, and other R&D functions.

Qualifications

  • Ph.D. in Pharmacokinetics, Pharmacology, Pharmaceutics or other relevant field with some experience in pharmaceutical industry, or M.D or Pharm.D. with equivalent experience.
  • Working knowledge of pharmacokinetics and modeling, PKPD principles, ADME concepts, and clinical pharmacology.
  • Proficient in using Phoenix WinNonlin, R, NONMEM, or other pharmacokinetic, modeling and data visualizations software.
  • Strong communication skills (verbal and written) and presentation skills are required. Excellent interpersonal skills and the ability to function in a highly matrixed team environment are essential.
#J-18808-Ljbffr

  • Italia Alnylam Pharmaceuticals Inc. A tempo pieno

    About Alnylam Pharmaceuticals Inc.We are a leading biotech company developing RNAi therapeutics. As part of our rapidly expanding clinical portfolio, we are seeking a highly skilled Senior Scientist to support our clinical pharmacology efforts.Job DescriptionThis is an exciting opportunity for a talented scientist to join our team and contribute to the...


  • Italia Antal International Network A tempo pieno

    Job Title:Senior Scientist for Nonclinical Safety and DMPKAbout the Role:We are seeking a highly skilled Senior Scientist to join our team in Nonclinical Safety and DMPK. As a key member of our team, you will provide support to ongoing and planned nonclinical programs at the early and late stages of drug development.Key Responsibilities:Lead non-clinical...


  • Italia Antal International Network A tempo pieno

    As a Senior Scientist Nonclinical safety and Drug Metabolism and Pharmacokinetics, you will provide support to ongoing and planned nonclinical programs at early and late stage of drug development. This position is open to hybrid working arrangements, however candidates with remote work arrangement will be considered. Responsability Lead non-clinical...

  • Data Scientist Senior

    3 giorni fa


    Italia NTT DATA Corporation A tempo pieno

    Responsibilities The ideal candidate as Senior Data Scientist in NTT DATA will have a mix of skills including Generative AI hands-on capability (preferably on Azure/GCP and on-premise), engineering best practices, statistical expertise, Machine and Deep Learning skills, and a strong business sense. The Senior Data Scientist will work with fellow data...


  • Italia Novartis Farmacéutica A tempo pieno

    Job Title: Senior Laboratory ScientistAbout the Role:We are seeking a highly skilled Senior Laboratory Scientist to join our team at Novartis Farmacéutica. As a key member of our laboratory team, you will be responsible for ensuring the efficient performance of laboratory activities and related investigations in compliance with GxP and HSE guidelines.Key...

  • Senior Data Scientist

    2 settimane fa


    Italia Ntt Data Corporation A tempo pieno

    Job SummaryThe ideal candidate for this Senior Data Scientist role at Ntt Data Corporation will have a mix of skills including Generative AI hands-on capability, engineering best practices, statistical expertise, Machine and Deep Learning skills, and a strong business sense. The Senior Data Scientist will work with fellow data scientists, data engineers, ML...

  • Senior Data Scientist

    5 giorni fa


    Italia Ntt Data Corporation A tempo pieno

    Job Summary: We are seeking a highly skilled Senior Data Scientist to join our team at Ntt Data Corporation. The ideal candidate will have a strong background in data science, machine learning, and engineering, with hands-on experience in Generative AI, statistical expertise, and a strong business sense.Key Responsibilities:Lead data science projects from...

  • Data scientist

    1 giorno fa


    Italia BeOptimized SRL A tempo pieno

    We're #hiring a new Data scientist (meteorology ) in European Union . Apply today or share this post with your network. CGS. Senior Data scientist (meteorology ). Data scientist (meteorology ), Clean Globe Staffing , European Union (Remote ) ... Data Scientist , HackerTrail - Recruitment Solutions, European Union (Remote ). Data scientist (meteorology...


  • Italia ClinChoice Inc. A tempo pieno

    At ClinChoice Inc., we are seeking a highly experienced Clinical Development Manager to join our team. As a key member of our clinical operations department, you will play a crucial role in overseeing the management of clinical trials from study design until study close-out.Main Responsibilities:Oversight and operational management of clinical trials,...


  • Italia ClinChoice Inc. A tempo pieno

    At ClinChoice Inc., we're seeking an experienced Senior Project Manager/Director to lead our global clinical trials management efforts. This is a unique opportunity to work directly with a single sponsor while enjoying the security and career growth opportunities that come with working for a global Contract Research Organization (CRO).The ideal candidate...


  • Italia ClinChoice Inc. A tempo pieno

    Are you interested in working directly for a single sponsor while having the security and additional career opportunities that working for a global CRO can bring? Our team says it’s the best of both worlds.... ClinChoice is searching for an experienced Senior Project Manager/Director to work with one of our pharmaceutical partners, to oversee Clinical...

  • Senior Data Scientist

    2 settimane fa


    Italia Bip - Business Integration Partners A tempo pieno

    La tua sfidaIl/la Senior Data Scientist in Bip gioca un ruolo cruciale nello sviluppo e implementazione di soluzioni avanzate di AI e Machine Learning, contribuendo alla trasformazione digitale delle più grandi aziende a livello internazionale.Nonostante il ruolo sia complesso, avrai l'opportunità di guidare progetti, collaborando strettamente con clienti...


  • Italia ClinChoice Inc. A tempo pieno

    Are you interested in working directly for a single sponsor while having the security and additional career opportunities that working for a global CRO can bring? Our team says it’s the best of both worlds.... ClinChoice is searching for an experienced Senior Project Manager/Director to work with one of our pharmaceutical partners to oversee Clinical...


  • Italia Barrington James A tempo pieno

    My client is a leading ophthalmic drug and device development company. They offer a comprehensive range of pre-clinical and clinical development services, leveraging their expertise and proven methods to bring innovative ophthalmic solutions to market. They value a diverse and inclusive workplace where kindness, excellence, joy, and scientific rigor are at...


  • Italia Bip - Business Integration Partners A tempo pieno

    Candidatura per il ruolo di Senior Data ScientistBip - Business Integration Partners, società leader nel settore dei servizi di integrazione e partnership, cerca un Senior Data Scientist per il suo team di analisti di dati.Descrizione del ruolo: Contribuire allo sviluppo di soluzioni di AI e Machine Learning per le più grandi aziende a livello...


  • Italia Regeneron A tempo pieno

    SUMMARY: We are seeking a Senior Manager of Global Patient Safety who will play a key scientific role in safety strategies for molecules in clinical development and post-marketing phases in the Ophthalmology Therapeutic Area. This includes safety data aggregation, review and analysis to support appropriate safety interpretation and benefit-risk assessment....

  • Senior Data Scientist

    3 giorni fa


    Italia Vodafone A tempo pieno

    Business Area: Local Vodafone Business Unit Date Posted: 7 Sep 2024 Full Time / Part Time: Full Time Contract Type: Permanent At Vodafone, we’re working hard to build a better future. A more connected, inclusive and sustainable world. As a dynamic global community, it's our human spirit, together with technology, that empowers us to achieve this. ...

  • Data Scientist Leader

    2 settimane fa


    Italia Vodafone A tempo pieno

    Job Title: Senior Data ScientistAbout the Role:We are seeking a highly skilled and experienced Senior Data Scientist to join our Analytics Platform & Solutions Squad team as Analytics Tech-Product Manager. As a key member of our team, you will be responsible for driving the development and evolution of our Vodafone Analytics portfolio.Key...


  • Italia Euraxess A tempo pieno 70.316 €

    Job DescriptionEuraxess seeks a highly skilled Senior DevOps Engineer/Computer Scientist to join its Information Technology Department.The selected candidate will focus on DevOps and computing infrastructure management within the scope of the International Gravitational Waves Network (IGWN) (EGO/Virgo, LIGO, KAGRA). This role is critical for streamlining...

  • Senior Research Scientist

    2 settimane fa


    Italia Physics World A tempo pieno

    Job SummaryThe Physics World team is seeking a highly skilled Senior Research Scientist to join our EPSI project. As a key member of our team, you will be responsible for the development and characterization of a X-ray detector for indirect dark matter search within the EPSI project.About the EPSI ProjectThe EPSI project aims to design, develop, and optimize...