Senior Scientist, Clinical Pharmacology Expert

2 settimane fa


Italia Alnylam Pharmaceuticals Inc. A tempo pieno
About Alnylam Pharmaceuticals Inc.

We are a leading biotech company developing RNAi therapeutics. As part of our rapidly expanding clinical portfolio, we are seeking a highly skilled Senior Scientist to support our clinical pharmacology efforts.

Job Description

This is an exciting opportunity for a talented scientist to join our team and contribute to the development of innovative RNAi therapeutics. The successful candidate will have a strong background in pharmacokinetics and pharmacodynamics (PKPD) and experience working with clinical data.

Main Responsibilities
  • Represent Clinical Pharmacology and provide PKPD support and guidance to clinical stage project teams.
  • Lead the analysis, interpretation, integration and reporting of clinical pharmacokinetic & pharmacodynamic data.
  • Conduct PK/PD analyses to guide development decisions on project teams.
  • Provide PKPD input for regulatory submissions such as briefing documents, IND, CTA and NDA.
  • Prepare appropriate documents or sections of clinical protocols, Investigator Brochures, Clinical Study Reports with respect to Clinical Pharmacology studies or data.
  • Preparation of abstracts and manuscripts for publication.
  • Closely partner with Research, Bioanalytical, Clinical functions, Regulatory, Project Management, and other R&D functions.
Requirements
  • Ph.D. in Pharmacokinetics, Pharmacology, Pharmaceutics or other relevant field with some experience in pharmaceutical industry, or M.D or Pharm.D. with equivalent experience.
  • Working knowledge of pharmacokinetics and modeling, PKPD principles, ADME concepts, and clinical pharmacology.
  • Proficient in using Phoenix WinNonlin, R, NONMEM, or other pharmacokinetic, modeling and data visualizations software.
  • Strong communication skills (verbal and written) and presentation skills are required. Excellent interpersonal skills and the ability to function in a highly matrixed team environment are essential.
Compensation

The salary for this position is estimated at around $145,000 - $170,000 per year, depending on location and experience. This is a competitive offer that reflects the importance of this role in supporting our clinical pharmacology efforts.



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