Investigation of the microbiota-immune system-brain tumor axis inpreclinical glioma models

Organisation/Company Sapienza Università di Roma- Dip. Fisiologia e Farmacologia Vittorio Erspamer Research Field Neurosciences Neurophysiology Researcher Profile Recognised Researcher (R2) Leading Researcher (R4) First Stage Researcher (R1) Established Researcher (R3) Application Deadline 5 Dec 2026 - 23:59 (UTC) Country Italy Type of Contract To be defined Job Status Not Applicable Is the job funded through the EU Research Framework Programme? Not funded by a EU programme Is the Job related to staff position within a Research Infrastructure? No

Offer Description

Research activity focus on investigating the interactions between the gut microbiota, the immune system, and glioma progression using preclinicalmouse models. Experimental procedures include fecal microbiota transplantation, pharmacological treatments, tumor growth monitoring, andassessment of neuroimmune responses. The project also involves cellular and molecular analyses through the isolation and characterization ofimmune cell populations, cell culture techniques, and functional cytotoxicity assays. In addition, bacterial extracellular vesicles and their role inmodulating anti-tumor immune responses are studied. Particular emphasis is placed on understanding the mechanisms underlying microbiota-braincommunication and the immune landscape of the tumor microenvironment.

Additional Information

Eligibility criteria

Degree grade: up to 10 points
Scientific publications relevant to the project topics: up to 10 points per publication (max 40 points)
Suitability of the curriculum to carry out the research activities envisaged by the project: up to 50 points
TOTAL 100 POINTS

• Italy

Eligibility of fellows: country/ies of residence:

• OTHER

Eligibility of fellows: nationality/ies: