Postdoc Position In Addressing Rna-Protein Interactions At The Molecular Scale Using An Advance[...]

1 settimana fa


GENOVA, Italia Istituto Italiano Di Tecnologia A tempo pieno

Postdoc position in Addressing RNA-protein interactions at the molecular scale using an advanced optical microscopy platform Commitment & contract: collaboration contract – up to 24 months Project: National Center for Gene Therapy and Drugs based on RNA Technology, Investimento 1.4 –" Potenziamento strutture di ricerca e creazione di "campioni nazionali di R&S" su alcune Key Enabling Technologies", Componente 2 "Dalla ricerca all'impresa" del Piano Nazionale di Ripresa e Resilienza. Location: CHT - IIT Genova - Erzelli WHO WE ARE At IIT we work enthusiastically to develop human-centered Science and Technology to tackle some of the most pressing societal challenges of our times and transfer these technologies to the production system and society. Our Genoa headquarter is strictly inter-connected with our 11 centers around Italy and two outer-stations based in the US for a truly interdisciplinary experience.

YOUR TEAM You will be working in a multicultural and multi-disciplinary research group headed by Prof. Alberto Diaspro, where experts collaborate towards the development of novel technologies and instruments for fundamental research in optics, life sciences and smart materials at the nanometer scale integrated with focused applications in oncology and neuroscience.

For this specific project, we aim to develop original and effective approaches to study RNA-protein interactions directed specifically towards our molecular candidates related to the remodeling of nuclear architecture and chromatin organization during neoplastic transformation/progression of Neuroblastoma (NB) cells.

We believe it is crucial to integrate the results obtained with this multidisciplinary approach (genetic engineering / molecular biology / biophysics) with an accurate evaluation, in the different stages of tumorigenesis, of the interactions of specific RNA transcripts in the selected chromatin domains with multiprotein complexes capable of determining structural epigenetic modifications of the chromatin using an advanced optical platform.

Within such framework we are looking for a Postdoc interested and able to contribute to the above reported research and endowed of a multidisciplinary background in the areas of genetic engineering, molecular and cellular biology, and nanoscale biophysics.

WHAT WOULD MAKE YOU SHINE PhD background with an interdisciplinary approach to key problems and topics regarding Applied Biology and Biophysics. Documented experience and skills to solve practical problems in biophysics including optical methods and genetic approaches. The ability to properly collect, analyze, report, organize and publish research data. Good command in spoken and written English. EXTRA AWESOME Experience on optical fluorescence microscopy with specific ability in sample preparation and bioimaging. Knowledge of Image processing and statistical software. Good communication skills. Strong problem-solving attitude. High motivation to learn. Spirit of innovation and creativity. Ability to work in a challenging and international environment. Ability to work independently and collaboratively in a highly interdisciplinary environment. COMPENSATION & BENEFITS Competitive salary package for international standards Private health care coverage Wide range of staff discounts WHAT'S IN FOR YOU? An equal, inclusive and multicultural environment ready to welcome you with open arms. We like contamination and encourage you to mingle and discover what other people are up to in our labs If paperwork is not your piece of cake, we got you There's a specialized team working to help you with that, especially during your relocation If you want your work to have a real impact, in IIT you will find an innovative and stimulating culture that drives our mission to contribute to the improvement and well-being of society If you feel this tickles your appetite for change, do not hesitate and apply

Please submit your application using the online form and including a detailed CV, university transcripts, cover letter (outlining motivation, experience and qualifications) and contact details of 2 references. Application's deadline: November 6th 2024.

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