Director, Drug Metabolism and Pharmacokinetics

6 mesi fa

Pomezia, Italia IRBM A tempo pieno

**Ref. 192A**

**Director, Drug Metabolism and Pharmacokinetics (DMPK)**:
With a history of contributing to several approved drugs, and its own internal pipeline of oncology and other therapeutic assets, IRBM is powered by deep collaborations and decades of expertise from leading global institutions. Our comprehensive in-house capabilities assist partners in achieving key milestones and progressing towards clinical readiness, positioning IRBM as a major player in driving innovation in the pharmaceutical and biotech fields.

**Key Responsibilities**:

- Represent pre-clinical DMPK on cross-functional development project teams and with external partners for small molecule, peptides and antibody therapeutics, including preparing project strategies and development plans.
- Ensure that the DMPK team is current with emerging concepts and technologies so that these tools can be applied as appropriate for issues resolution.
- Implement/manage quantitative bioanalysis of plasma and other biological matrices to support pharmacokinetic, toxicokinetic and in vitro ADME analyses of novel therapeutics.
- Oversee internal and outsourced pre-clinical drug metabolism and PK activities on multiple projects, including study design, data interpretation, report preparation.
- Provides strong scientific and strategic leadership, urgency, and business acumen to grow and progress IRBM mission in a speedy manner.

**Competencies/skills**:

- Guides personnel goal setting to the most productive pursuit of shared goals and strategies.
- Supervising and managing a team of scientists by mentoring them, as well as providing expert advice and context for the interpretation of complex data.
- Manages personnel performance and develops career growth opportunities across DMPK.
- Desing and implement resourcing plans, draft-budgets, manages approved budgets and oversees hiring activities.
- Oversees regular review of staff deployment and project status, to ensure all projects are appropriately prioritized and resourced, and key goals and timelines are met.
- Balances degree of innovative exploration with pursuit of defined project objectives, and coordinates acquisition of new scientific capabilities, as appropriate
- Strong intellectual leadership, Capable of working autonomously and collaboratively in a multidisciplinary team setting.
- Strong verbal, written communication and relationship skills including success managing collaborations; track record of successful problem-solving, high-quality science and influencing of stakeholders, particularly in a drug project context.

**Requirements**:

- PhD or equivalent degree in Pharmaceutical Sciences, Molecular Biology, Chemistry, Biochemistry or Pharmacology with experience in drug discovery, or a higher degree in a research area relevant to DMPK science.
- At least 8+ years of relevant industry experience.
- IRBM considers all qualified applicants without discrimination, including on the basis of race, gender, age, disability, gender identity or expression, national origin, religion, sexual orientation, or other protected classes. We nurture an inclusive culture where everyone can show their full potential and enjoy a fulfilling career._

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