mRNA Process Development Scientist
2 giorni fa
We are seeking a highly skilled mRNA Process Development Scientist to join our team at Thermo Fisher Scientific.
Key Responsibilities- Develop and optimize downstream processes for mRNA purification using liquid chromatography and TFF.
- Conduct feasibility assessments, technical consultations, training, and bench trials to support process development.
- Collaborate with cross-functional teams to identify and implement process improvements.
- Scaled up/scale down testing plans and data review, sizing, compatibility, and solving technical issues.
- Support technology transfer to the cGMP manufacturing and quality control (QC) groups for clinical material production/analysis.
- Train junior scientists as needed.
- Stay up-to-date with new technologies and scientific literature to drive innovation.
- Master's Degree in Life Sciences, Chemical, Biological or Process Engineering with proven experience in the Biopharmaceutical industry.
- PhD in Biochemistry/Chemistry/Chemical Engineering/ Biological Engineering or related scientific subject areas with +2 years of relevant post-doctoral or industrial experience.
- Knowledge of main purification techniques used for drug manufacturing.
- Experience in process development for therapeutics with standard downstream purification techniques.
- Experience with GLP and GMP compliance and manufacturing preferred.
- Excellent communication and presentation skills.
- Ability to multi-task and prioritize to meet deadlines.
- Experience applying U/HPLC, FPLC, CGE, Ribogreen assay and DLS.
- Technical expertise in mRNA synthesis by enzymatic method development.
Thermo Fisher Scientific is an Equal Opportunity Employer.
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