mRNA Process Development Scientist

2 giorni fa


Monza, Lombardia, Italia Thermo Fisher Scientific A tempo pieno
About the Role

We are seeking a highly skilled mRNA Process Development Scientist to join our team at Thermo Fisher Scientific.

Key Responsibilities
  • Develop and optimize downstream processes for mRNA purification using liquid chromatography and TFF.
  • Conduct feasibility assessments, technical consultations, training, and bench trials to support process development.
  • Collaborate with cross-functional teams to identify and implement process improvements.
  • Scaled up/scale down testing plans and data review, sizing, compatibility, and solving technical issues.
  • Support technology transfer to the cGMP manufacturing and quality control (QC) groups for clinical material production/analysis.
  • Train junior scientists as needed.
  • Stay up-to-date with new technologies and scientific literature to drive innovation.
Requirements
  • Master's Degree in Life Sciences, Chemical, Biological or Process Engineering with proven experience in the Biopharmaceutical industry.
  • PhD in Biochemistry/Chemistry/Chemical Engineering/ Biological Engineering or related scientific subject areas with +2 years of relevant post-doctoral or industrial experience.
  • Knowledge of main purification techniques used for drug manufacturing.
  • Experience in process development for therapeutics with standard downstream purification techniques.
  • Experience with GLP and GMP compliance and manufacturing preferred.
  • Excellent communication and presentation skills.
  • Ability to multi-task and prioritize to meet deadlines.
Desirable Skills
  • Experience applying U/HPLC, FPLC, CGE, Ribogreen assay and DLS.
  • Technical expertise in mRNA synthesis by enzymatic method development.
About Us

Thermo Fisher Scientific is an Equal Opportunity Employer.



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