mRNA Process Development Scientist
6 giorni fa
Job Summary
We are seeking a highly skilled mRNA Process Development Scientist to join our team at Thermo Fisher Scientific. As a key member of our biopharmaceutical development team, you will be responsible for the development and optimization of downstream processes for mRNA products.
Key Responsibilities
- Develop and optimize downstream processes for mRNA products using liquid chromatography and tangential flow filtration (TFF)
- Conduct feasibility assessments, technical consultations, training, and bench trials to support process development
- Collaborate with cross-functional teams to develop and implement scalable downstream processes
- Support technology transfer to cGMP manufacturing and quality control groups
- Perform routine bench work and prioritize responsibilities effectively
Qualifications
- Master's degree in Life Sciences, Chemical, Biological, or Process Engineering with experience in the biopharmaceutical industry
- PhD in Biochemistry, Chemistry, Chemical Engineering, or Biological Engineering with relevant post-doctoral or industrial experience
Requirements
- Knowledge of main purification techniques used for drug manufacturing
- Experience in process development for therapeutics with standard downstream purification techniques
- Familiarity with GLP and GMP compliance and manufacturing
- Excellent communication and teamwork skills
Preferred Qualifications
- Expertise in upstream processing, including bioreactors and bio reactions optimization
- Experience applying U/HPLC, FPLC, CGE, and DLS
- Technical expertise in mRNA synthesis by enzymatic method development
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