mRNA Process Development Scientist

6 giorni fa


Monza, Lombardia, Italia Thermo Fisher Scientific A tempo pieno

Job Summary

We are seeking a highly skilled mRNA Process Development Scientist to join our team at Thermo Fisher Scientific. As a key member of our biopharmaceutical development team, you will be responsible for the development and optimization of downstream processes for mRNA products.

Key Responsibilities

  • Develop and optimize downstream processes for mRNA products using liquid chromatography and tangential flow filtration (TFF)
  • Conduct feasibility assessments, technical consultations, training, and bench trials to support process development
  • Collaborate with cross-functional teams to develop and implement scalable downstream processes
  • Support technology transfer to cGMP manufacturing and quality control groups
  • Perform routine bench work and prioritize responsibilities effectively

Qualifications

  • Master's degree in Life Sciences, Chemical, Biological, or Process Engineering with experience in the biopharmaceutical industry
  • PhD in Biochemistry, Chemistry, Chemical Engineering, or Biological Engineering with relevant post-doctoral or industrial experience

Requirements

  • Knowledge of main purification techniques used for drug manufacturing
  • Experience in process development for therapeutics with standard downstream purification techniques
  • Familiarity with GLP and GMP compliance and manufacturing
  • Excellent communication and teamwork skills

Preferred Qualifications

  • Expertise in upstream processing, including bioreactors and bio reactions optimization
  • Experience applying U/HPLC, FPLC, CGE, and DLS
  • Technical expertise in mRNA synthesis by enzymatic method development


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