Senior Technician/Technician Of Multi-Omics Technologies

APPLICATION CLOSING DATE: 17th of June 2024 The Human Technopole Foundation is looking for a Senior Technician of Multi-omics Technologies for the IU2 Multi-Omics Technologies unit of the National Facility for Genomics.
The National Facility for Genomics provides state-of-the-art and innovative services in genomics. Its core mission is to implement robust experimental and analytical workflows to probe all major domains of genomic exploration, including but not limited to the analysis of DNA, RNA, chromatin and other markers of epigenetic and regulatory activity. These techniques can be applied to diverse areas of biology, with resolution spanning to whole organisms, to tissues or individual cells. Overall, NF Genomics aims to empower research in all domains of genomics for the Italian scientific community at large.

The National Facilityfor Genomics foresees four Infrastructural Units (IU):
UI1 High Throughput Sequencing mainly focused on providing state-of-the-art high-throughput sequencing services. This dedicated unit specializes in delivering top-tier genomics, transcriptomics, and epigenomics analyses, employing the latest protocols for sample processing and sequencing.
UI2 Multi-Omics Technologies specialized in multi-omics technologies. Its focus extends to providing cutting-edge services in single-cell and spatial multi-omics analysis, as well as long-read sequencing. This Unit closely collaborates with the Tissue Processing Unit and NF-Imaging, specifically dedicated to implementing spatial transcriptomics protocols.
UI3 Technology Development stays at the forefront of innovation, this dedicated team is committed to methods and technology development. The highly qualified staff is continuously engaged in the evaluation of new technologies and instruments, considering them for acquisition into our facility. We specialize in the optimization and scale-up of custom experimental protocols, offering these services to the broader scientific community.
UI4 Computational Genomics is the computational core of the NF Genomics, the team is dedicated to developing, implementing, and maintaining automated pipelines for the pre-processing and primary data analysis of sequencing data. This unit closely collaborates with the NF for Data Handling and Analysis.
In the context above outlined, the Senior Technician of Multi-omics Technologies, reporting directly to the Senior Manager of the IU2, will become part of the team of the Multi-Omics Technologies unit of the National Facility for Genomics. At Infrastructural Unit 2, we work at the forefront of innovation in multi-omics research. We employ state-of-the-art technologies and protocols for multi-omics analysis, continually pushing boundaries by implementing and applying innovative methods. Our commitment to staying ahead in this dynamic field ensures that our external and internal users benefit from the latest advancements and methodologies. Infrastructural Unit 2 works in tandem with IU 4 and the NF for Data Handling and Analysis. This strong interaction is pivotal in setting up and developing new methods and bioinformatic analysis pipelines.


Key tasks and responsibilities Handle sample and library preparation, including through automation-intensive workstations.Manage data collection and evaluation support, including the use of a LIMS for data and sample tracking.Handle next-generation sequencing data, including storage of data and metadata and preparation of sequencing-related files.Support in the development and implementation of SOPs and/or experimental pipelines.Participate in key aspects of general Facility management and organization (e.g., managing inventories and stocks of samples, reagents, equipment, and materials).Report regularly with colleagues and line manager on the flow and timeline of sequencing projects.Participate in implementation of single cell sequencing technologies and spatial-omics platforms as technology progresses. Mandatory requirements: Master's degree in a relevant subject, e.g., molecular biology, genetics, biochemistry, or in a related field of the life sciences.Excellent technical and working knowledge of multiple single-cell and/or spatial-omics technologies (+3 years of hands-on experience), including documented experience in preparation of libraries for the main single cell sequencing and/or spatial-omics technologies (eg. 10x Genomics, Nanostring);Fluency in English – HT is an international research institute.Preferred requirements Experience with single molecule sequencing technologies (i.e. Nanopore sequencing).Experience with Histology and Imaging techniques.Good working knowledge of bioinformatics tools to handle, store and prepare files from genomics data.Organizational and social skills: Excellent attention to detail, organizational skills, proactive attitude to solve problems and ability to work to deadlines.Proven communication, team building, and problem-solving skills.Excellent organizational, communication skills and work ethic.Ability to independently develop, optimize and deploy research support, as a member of a closely collaborative team.Application Instructions Please apply by sending:
i) a CV
ii) a motivation letter in English
iii) names and contacts of at least 2 refereesQuestions concerning the role and any queries regarding the terms and conditions should besent to ******(terms and conditions) (these email address should not be usedto send applications). Why Human Technopole HT seeks scientific excellence, we recruit the best scientific talents through international, open calls;Our working environment is international, friendly and inclusive. Our scientists work together across disciplines on research topics of biomedical relevance, leveraging synergies between their diverse skillsets and methodological approaches;We believe that highly diverse teams yield the best and most innovative results;We engage in outward-facing scientific activities aimed at benefiting the national and international research community. Training is also at the heart of our activity, with initiatives and opportunities for our staff, including scientific courses, conferences and workshops.Main benefits Welfare plans.Canteen service.Work-life balance provisions.Italian language training for foreigners.Maternity leave up to 1 year and other support for new parents.Counseling.Flexible working hours.Remote working policy.Support for relocation.Special consideration will be given to candidates who are part of the protected categories list, according to L. 68/99. Number of positions offered: 1
Contract offered: CCNL Chimico Farmaceutico, Fixed-term -3 years with possibility of renewal-- employee level
Salary indication:up to 41.400 (RAL) depending on the seniority.Tax benefits where applicable.
The position is based in Milan

"The Foundation reserves the right, at its sole discretion, to extend, suspend, modify, revoke, or cancel this job posting without giving rise to any rights or claims whatsoever in favor of the candidates; the Foundation reserves, however, the right not to proceed with the awarding of the above-described assignment due to the effect of supervening regulatory provisions and/or obstructive circumstances".

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