Technician of The Biostatistics Unit

2 settimane fa


Milano, Italia Human Technopole A tempo pieno

**APPLICATION CLOSING DATE: 26th of February 2024**

The Human Technopole is looking for a **Technician **(statistician/statistical geneticist) **of the Biostatistics Unit **for the** Centre for Genomics - Population and Medical Genomics Programme.**

Human Technopole (HT) is a new interdisciplinary research institute in Milan, Italy, created and supported by the Italian government whose aim is to develop innovative strategies to promote human health through a multidisciplinary and integrated approach, combining genomics, computational and structural biology, neuroscience, and data and decisions sciences. The Population and Medical Genomics Programme is part of the Genomics Research Centre, and will deploy large-scale genomic analyses to study the genetic basis of human traits and diseases.

We are looking for a **Technician **of **the **Biostatistics** Unit**, a new state-of-the-art unit for the statistical analysis of genetic data from human populations. This newly created unit will support the data analysis efforts of the research groups in the Population and Medical Genomics Programme. The unit will work with research teams in a collaborative fashion, performing statistical analysis on a variety of genomics data types. The unit will rely on data generated by the research teams, the Cellular Technologies Unit and the Genomics Core Facility of HT. The unit will also be involved in the analysis of data generated by external collaborators and publicly available data when required. The Unit will benefit from a large High-Performance Computing and Data Storage infrastructure, and from close interaction with an expert community of computational biologists within the Genomics Centre, other Research Centres, and of core facilities at HT.

A key mission of the **Technician of the **Biostatistics Unit **will be to carry out advanced statistical analyses of genetic data in order to produce reliable and reproducible results useful to carry forward the work within the centre and the institute in general.

**Key tasks and responsibilities**

The **Technician of the Biostatistics Unit** for the Centre for Genomics - Population and Medical Genomics Programme will:

- Analyze data from healthy volunteers and patient samples and provide results and QC to the relevant researchers in the centre;
- Contribute to new statistical genetics methods development for reconstructing the causal path from genetic variant to disease and functional genomics data.
- Curate and release genetic datasets generated by pipelines;
- Contribute to handling of the genetic and phenotypic datasets produced within the unit and through our partners;
- Help accessing and analysing public datasets that may be relevant to the centre’s activities;
- Contribute to import, storage and use of external datasets, including access rights and storage of phenotypic data.

**Mandatory Requirements**:

- +1 years of hands-on experience in biostatistics, statistical genetics or machine learning applied to human population data;
- Fluency in English - HT is an international research institute;
**Preferred requirements**
- Experience with analyzing large omics data sets (ie expression or proteomics data)
- Capability in using tools for version control tools (ie. GitHub)
- Good coding skills in one of the commonly used statistical analysis languages, ideally R or Python.
- Documented experience with using common statistical genetics software (ie. Regenie, plink, GCTA);
- Documented experience in the analysis of large-scale genetic datasets involving human samples;
- Excellent computational skills, outstanding programming abilities and trouble-shooting;
- HPC and Unix systems savvy.

**Organizational and social skills**:

- Ability to interact effectively with other teams and work synergistically to drive projects forward;
- Highly organized and meticulous.

**Application Instructions**

i) a CV
ii) a motivation letter in English
iii) names and contacts of at least 2 referees

**Why Human Technopole**
- HT seeks **scientific excellence**, we recruit the best scientific talents through international, open calls;
- Our working environment is **international**, **friendly** and **inclusive**. Our scientists **work together across disciplines** on research topics of biomedical relevance, **leveraging synergies** between their diverse skillsets and methodological approaches;
- We believe that **highly diverse teams yield the best and most innovative results;**:

- We engage in **outward-facing scientific activities** aimed at benefiting the national and international **research community. **Training is also at the heart of our activity, with initiatives and opportunities for our staff, including scientific courses, conferences and workshops.

**Main benefits**
- Welfare plans.
- Canteen service.
- Work-life balance provisions.
- Italian language training for foreigners.
- Maternity leave up to 1 year and other support for new parents.
- Counseling.
- Flexible working hou


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