Postdoctoral Researcher in Nanoparticle-Based Cancer Treatment

1 mese fa


Genoa, Liguria, Italia Istituto Italiano di Tecnologia A tempo pieno
Project Overview

We are seeking a highly motivated Postdoctoral Researcher to join our team at the Istituto Italiano di Tecnologia (IIT) in Genova, Italy. The successful candidate will be part of the Research Line of Polymers and Biomaterials, headed by Prof. Nicola Tirelli, and will collaborate with the center of Genomic Science, headed by Dr. Francesco Nicassio.

Research Focus

The AIRC project aims to develop hyaluronic acid (HA)-based nanoparticles for the delivery of non-coding RNA and other payloads. The successful candidate will work on the in vitro assessment of efficacy of the RNA-loaded nanomaterials in complex in vivo models, as well as the evaluation of the nanomaterials in non-tumour bearing murine models.

Responsibilities
  • Design and execute experiments to evaluate the efficacy of RNA-loaded nanomaterials in in vitro and in vivo models
  • Collaborate with the center of Genomic Science to develop and optimize non-coding RNA constructs
  • Work with the Research Line of Polymers and Biomaterials to develop and characterize HA-based nanoparticles
  • Contribute to the development of pharmacokinetic studies and in vitro 3D cellular models
Requirements
  • PhD in cancer studies, pharmacology, drug delivery, or cognate discipline
  • Experience in working with small laboratory animals and in particular with IV administration
  • Experience in histology and ex vivo techniques (incl. fluorescence microscopy, blood analysis)
  • Experience in mammalian cell culture and in standard cell biology techniques (PCR, Western, flow cytometry)
What We Offer
  • Competitive salary package for international standards
  • Private health care coverage
  • Wide range of staff discounts
  • Candidates from abroad or Italian citizens who permanently work abroad and meet specific requirements, may be entitled to a deduction from taxable income of up to 90%
About IIT

IIT is a non-profit research institute that aims to develop human-centered Science and Technology to tackle some of the most pressing societal challenges of our times. Our Genoa headquarters are strictly interconnected with the other 11 centers around Italy and two outstations based in the US. We promote excellence in basic and applied research such as neuroscience and cognition, humanoid technologies and robotics, nanotechnology, materials for a truly multidisciplinary scientific experience.



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