Postdoctoral Researcher in Nanoparticle-Based Cancer Treatment

4 settimane fa


Genoa, Liguria, Italia Istituto Italiano di Tecnologia A tempo pieno
Project Overview

The AIRC (Associazione Italiana per la Ricerca sul Cancro) IG2020 project "Hyaluronic acid-based carriers. Targeting mechanisms and application in a combination therapy approach" aims to develop hyaluronic acid (HA)-based nanoparticles for the delivery of non-coding RNA and other payloads. The project focuses on the in vitro and in vivo assessment of the efficacy of the RNA-loaded nanomaterials in complex in vivo models.

Job Description

We are seeking a highly motivated Postdoctoral Researcher to join our team at the Istituto Italiano di Tecnologia (IIT) in Genova. The successful candidate will be part of the Research Line of Polymers and Biomaterials, headed by Prof. Nicola Tirelli, and will collaborate with the center of Genomic Science, headed by Dr. Francesco Nicassio.

Responsibilities
  • Design and develop HA-based nanoparticles for the delivery of non-coding RNA and other payloads
  • Conduct in vitro and in vivo experiments to assess the efficacy of the RNA-loaded nanomaterials
  • Evaluate the pharmacokinetics, biodistribution, and degradation of the nanoparticle components and payloads
  • Collaborate with the research team to develop and implement new experimental approaches
Requirements
  • PhD in cancer studies, pharmacology, drug delivery, or a related field
  • Experience in working with small laboratory animals and in vitro techniques
  • Experience in histology and ex vivo techniques, including fluorescence microscopy and blood analysis
  • Experience in mammalian cell culture and standard cell biology techniques, including PCR, Western, and flow cytometry
What We Offer
  • Competitive salary package
  • Private health care coverage
  • Wide range of staff discounts
  • Opportunity to work in a dynamic and multicultural environment
How to Apply

If you are a motivated and experienced researcher looking for a new challenge, please submit your application, including your CV and a cover letter, to [insert contact information].



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