mRNA/LNP Process Development Scientist

1 settimana fa


Monza, Lombardia, Italia Thermo Fisher Scientific A tempo pieno
Job Summary

We are seeking a highly skilled mRNA/LNP Process Development Scientist to join our team at Thermo Fisher Scientific. As a key member of our biopharmaceutical development team, you will be responsible for leading the development and implementation of mRNA/LNP processes.

Key Responsibilities
  • Participate in cross-functional teams to drive project success and lead problem-solving initiatives.
  • Design and execute experimental plans, analyze data, and develop high-quality reports.
  • Build and maintain strong relationships with customers through technical interactions.
  • Lead activities in mRNA/LNP expertise and provide solutions to identify process risks and issues.
  • Contribute to process improvements and implement innovative technologies.
  • Demonstrate flexibility to support activities within the department.
Qualifications

A Master's Degree in a life science, chemical, biological, or process engineering field, or equivalent experience, with 5+ years of confirmed experience in the biopharmaceutical industry, preferably in a process development role. Alternatively, a PhD in biochemistry, chemistry, chemical engineering, biological engineering, or a related scientific field, or equivalent experience, with +2 years of relevant post-doctoral or industrial experience.

Key Requirements
  • Experience with biomolecule purification techniques, including HPLC/FPLC chromatography, tangential flow filtration, and other filtration techniques.
  • Knowledge of technology transfer and GMP manufacturing.
  • Implementation of DoE studies and high-throughput screening for purification processes.
  • Understanding of in vitro transcription critical process parameters, reaction optimization, and scale-up.
  • Experience in manufacturing large mRNA molecules, including self-amplifying and circular RNAs.
  • Understanding of the mRNA-LNP encapsulation process scale-up and execution of relevant associated analytical methods.
  • Proven track record of efficiently working in a fast-paced and multifaceted environment.
Company Overview

Thermo Fisher Scientific is an Equal Opportunity Employer committed to diversity and inclusion. We are a leading provider of scientific instrumentation, reagents, and services for a wide range of industries, including biopharmaceuticals, diagnostics, and life sciences.



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